Day 1 :
Professor of Environmental Engineering University of Southern California
Keynote: Pro-inflammatory responses to airborne ultrafine nanoparticles from airport and urban traffic emissions
Time : 10:00-10:45
Prof Constantinos Sioutas has completed his PhD in 1994 at Harvard. He is the Fred Champion Professor of Environmental Engineering at the University of Southern California and the director of the aerosol group. He has published more than 350 papers in reputed journals and has been serving as an editorial board of several journals including Science of Total Environment and Atmospheric Environment.
Air traffic is rapidly growing, raising concerns about the air pollution in the surroundings of airports and its impact on public health. However, little is known about the impact of air pollution sources on air quality and health in the vicinity of airports. In this study, the sources and adverse health effects of airport-related ultrafine particulate matter (PM) were investigated and compared to those of urban traffic emissions. Ambient nanoparticles (PM0.25, smaller than 250nm) were collected at the Los Angeles International Airport (LAX) and at a central Los Angeles site (USC campus), along with nanoparticles collected directly from turbine and diesel engines. The particle chemical composition, oxidative potential (OP) (ascorbic acid (AA), and electron spin resonance (ESR) assay) as well as their reactive oxygen species (ROS) activity, inflammatory potential (interleukin (IL) 6 and 8 and tumor necrosis factor (TNF) –α) and cytotoxicity on human bronchial epithelial (16HBE) cells were assessed. Chemical composition measurements confirmed that aircraft emissions were the major source to LAX nnaoparticles, while the sources of the USC samples were more complex, including traffic emissions, suspended road and soil dust, and secondary aerosols. The traffic-related transition metals (Fe and Cu) in LAX and USC samples mainly affected OP values of particles, while multiple factors such as composition, size distribution and internalized number of particles contributed to the promotion of ROS generation in 16HBE cells during 4 h exposure. Internalized particles in cells might also play an important role in activating inflammatory responses during cell recovery period, with LAX particles being more potent. Our results demonstrated considerable toxicity of airport-related particles, even at low exposure concentrations, suggesting that airport emission as source of nanoparticles may also contribute to the adverse effects on public health attributable to PM. The potency of such particles is in the same range as those collected at a site in urban area impacted heavily by traffic emissions.)
IIT Bombay ( Retd.) Chairman SSPC India
Time : 10:45-11:30
Prof. A.S.Khanna, full professor Indian Institute of Technology, Bombay. He also worked as Deputy Director, IIT Indore for 7 months on Deputation from IIT Bombay. He is in Metallurgy at Indian Institute of Technology, Bombay for almost 22 years. He joined IIT Bombay in 1991, after completing 15 years as Scientific officer, IGCAR, Kalpakkam, fast Reactor project of Atomic Energy. He is specialist in High Temperature Corrosion, high temperature coatings, organic coatings and surface modifications. He has guided more than 13 students and another 10 students are working under his guidance for Ph.D at IIT Bombay. Prof. Khanna has more than 36 years of experience on various aspects of corrosion. He has more than 250 publications in reputed International Journals and Conference proceedings and chapters in books. He has written two books, published by ASM International and Woodhead publicartion, UK. And edited four books.
There is almost a new application of Graphene being discussed everyday, Whether, it is in electronics to enhance the memory of micro-devices, increase in the efficiency of batteries, water filtration or to make room air-heaters, Graphene is capable of creating the new application. We have worked on new applications of Graphene in making advanced coatings, suitable for highly aggressive environments or creating a new thinnest coating on automobiles or coil coatings or to create highly conductive coating. We have already filed a patent on the development of highly conductive coatings using graphene. However, the main limitation is the availability of pure and defect free Graphene in large industrial scale quantity. Though, there are various methods to prepare graphene based on treatment using strong acids, high shear exfoliation method, CVD and many others, we have used a new method called Pressure Exfoliation method to make industrial scale Graphene. It is a totally eco-friendly method without use of any strong chemical or heat and the product formed is with a yield of 15%. The Graphene prepared is 3-4 layer thick. We have used the Graphene prepared using this method to make thin Graphene coatings which has strong corrosion and erosion resistance. We also used the Graphene as a anti-corrosion pigment to replace zinc in zinc based primers and made conductive coatings with conductivity of 11 S/cm. Several applications have been made on industrial buildings and performance has been found excellent.
Associate Professor in East Tennessee State University
Keynote: Superacidic nanostructured materials for catalytic alkylation of aromatic compounds by alkenes
Time : 11:30-12:15
Aleksey Vasiliev has his expertise in Material Science, Organic Chemistry and Catalysis. He has completed his PhD from the Institute of Bioorganic Chemistry and Petrochemistry in Ukraine. Then he continued his professional career in the National Technological University in Argentina, and further moved to Rutgers University (USA). Currently, he occupies the position of an Associate Professor in East Tennessee State University. In recent years, he worked in the field of mesoporous materials and their applications in adsorption and catalysis.
To the present time, superacidic nanostructured materials found many applications in chemical industry, medicine and environmental protection. They are used as efficient heterogeneous catalysts of environmentally friendly manufacture of numerous organic products. The objective of this work was to develop a low-waste catalytic synthesis of long-chain alkylbenzenes, which are important intermediates in the manufacture of anionic surfactants. Currently, they are produced by Friedel-Crafts alkylation of benzene using Lewis acids. This approach poses a serious threat to the environment due to generation of large volume of toxic waste. This problem was solved by the use of phosphotungstic acid (PTA) covalently immobilized on the surface of silica gel. PTA is a well-known catalytically active superacid with pKa ≈ -13. Superacidic catalysts were synthesized by co-condensation of tetraethyl orthosilicate with PTA in acidic media. Various surfactants were used as pore-forming agents. FT-IR spectra of the solid products contained characteristic band of PTA. TEM images revealed mesoporous structure of the catalysts and the presence of embedded PTA clusters. Mesoporous materials had high BET surface area and high concentration of easily accessible acidic catalytic sites. Obtained catalysts were successfully tested in liquid-phase alkylation of 1,3,5-trimethylbenzene by dec-1-ene at various temperatures. The catalyst synthesized with Pluronic P123 as a template demonstrated the highest activity in the conversion of dec-1-ene into alkylbenzenes. High thermal and chemical stability of the obtained mesoporous materials also enabled their recyclability. Catalysts remained active during three subsequent cycles of alkylation.
National Tsing Hua University, Taiwan
Keynote: In Vitro Fertilization on a Chip
Time : 12:15 - 1:00
Dr. Da-Jeng Yao is a Professor at Department of Power Mechanical Engineering and Institute of NanoEngineering and MicroSystems (NEMS), also an adjunct Professor at Department of Engineering and System Science, National Tsing Hua University, Taiwan. He received his MS from Department of Mechanical Engineering, Lehigh University in 1996, and Ph.D. from Department of Mechanical and Aerospace Engineering, University of California at Los Angeles (UCLA) in 2001. More than 80 journal papers were published at top journals. He got Wu-Da-Yu Memorial Award (Young Investigator) from National Science Council in 2009, National Innovation Award in both 2012 and 2014, and Nanoscience Award by Publishing Division of Cognizure in 2015. He was awarded as ASME fellow since 2013, IEEE senior member since 2014, and RSC fellow since 2018.
The in vitro fertilization (IVF) is an important technique in biological and clinical studies since 1970. In recent years, microfluidic system has been widely used in cell detection or position a single-cell level, including the mechanical, optical, electromagnetic fields due to the advantages of biocompatibility, high-precision, low-cost, disposable, and easy to reproduce etc. In this presentation, we propose three different types of microfluidic systems, the imitation oviduct microfluidic chips, to enhance the probability of embryo fertilization for Oligozoospermia patients. At the first of the continued microfluidic chip, the motile sperms from the oligozoospermia patients can be separated by using microfluidic chip based on its laminar flow. Then to imitate the oviduct, the oocyte can be effectively position by dielectrophoresis (DEP) technology, and it will be reacted with those motile sperms to form embryo under proper cultural environment. Finally, the reacted oocyte, embryo, was moved to incubator for further culture. The embryo can be cultured successfully after three and an half day, that is comparable with the one by using traditional IVF. In contract with continued microfluidic system, two types of droplet-based microfluidic system would be presented. The dynamic culture is demonstrated with a system for EWOD that can manipulate a single droplet containing one mouse embryo to mimic the path from an oviduct to a uterus. A static mouse embryo culture on EWOD chips is presented for comparison with the results of dynamic culture. According to the dynamic and static results, the rate of embryo cleavage to hatching blastocyst with a dynamic culture is greater than that with a static culture. The EWOD system can enhance the culture of mouse embryos in a dynamic environment. Another dropletbased microfluidic system will also be shown, not just only for the embryo droplet formation from sperms and oocyte, but further for dynamic culture and embryo diagnostic in the microchannel.